Abstract: Objective To test the effect of sweetsop peel extracts on chicken cellular immunity and humoral immunity.Methods The experimental and control immunized with chicken infectious laryngotracheitis SA_2 vaccine and egg-drop syndrome inactivated oil-adjuvant vaccine chickens were injected with sweetsop peel extracts and saline respectively.After vaccination,leukocytes were isolated and sera were separated from the vain blood collections.The lymphocyte transformation test and hemagglutination-inhibition test were taken.Results The lymphocyte transformation rate of experimental group was much higher than that of control.There was significant differences in statistics between the experimental and control groups(P<0.01).The increase of titer in hemagglutination-inhibition was low,even in negative values,and there was no significant differences between the experimental and control groups(P>0.05).Conclusion The extracts of sweetsop peel possessed the active effect on chicken cellular immunity and no effect on homoral immunity.

Key words: Sweetsop peel extracts, Cellular immunity

摘要： 目的检测番荔枝果皮提取物对鸡细胞免疫及体液免疫的影响。方法用鸡传染性喉气管炎SA2株弱毒疫苗和减蛋综合症灭活油佐剂疫苗免疫接种实验鸡后,分别用番荔枝果皮提取物和生理盐水注射实验组和对照组。免疫后静脉采血分离白细胞及血清,进行淋巴细胞转化实验及血凝抑制实验。结果实验组的淋巴细胞转化率明显高于对照组,数理统计说明实验组与对照组具有极显著性差异(P<0.01);而血凝抑制效价在增长率上的变化很低,甚至有负增长的现象,数理统计实验组和对照组之间不具有显著性差异(P>0.05)。结论番荔枝果皮提取物对鸡的细胞免疫具有积极作用,而对鸡的体液免疫没有影响。

关键词: 番荔枝果皮提取物, 细胞免疫, 体液免疫