Abstract: Abstract: To create experimental model for neurotropic regeneration research of the multi-branch facial nerve defect． Method Twelve rabbits were used in this study． The rabbit’s facial nerve was explored and cut near the crotch，leaving a 5 mm gap． Then，the gap was repaired by multi-branch chitosan chamber． 1，2，3，8，16，24 weeks later，ethology of the rabbit’s face was evaluated． Ｒesult Eleven rabbits were still alive，24 weeks after the operation． Swell or rejection was not found． Conclusion The experimental model is stable and reproducible． Tthe use of multi-branch chitosan conduits for nerve regeneration study is feasible．

Key words: experimental animal, rabbit, nerve regeneration, facial nerve

摘要： 摘要: 目的 探索建立面神经多分支缺损后趋向性再生动物模型的可行性。方法 新西兰兔 12 只，手术造成面神 经干和所有分支 5 mm 缺损动物模型，用多分支壳聚糖导管修复，分别于术后 1、2、3、8、16、24 周观察面部行为学。 结果 11 只动物存活至术后 24 周，术区未出现肿胀、破溃、排异等现象。结论 该修复模型稳定，可重复性强，多 分支壳聚糖导管做神经再生室用于研究神经趋向性再生是可行的。

关键词: 实验动物, 兔, 神经再生, 面神经