Abstract: With the development of biotechnology and biomedicine, the demand for the use of laboratory animals has increased, creating an urgent need to develop new experimental animal resources with greater potential. Myodes rufocanus and Apodemus peninsulae are wild rodent species, both recognized as forest noxious animal with a broad distribution. Based on current research, we have already obtained a general understanding of the biological characteristics of Myodes rufocanus and Apodemus peninsulae, advancing their development as experimental animals. This paper systematically summarizes existing research progress on these two species from five disciplinary perspectives: genetics, microbiology, parasitology, ethology and laboratory animal domestication. This synthesis aims to provide a theoretical foundation for the future expansion of experimental animal resources and for the development of animal models of human diseases.

Key words: Myodes rufocanus, Apodemus peninsulae, experimental animal resources

摘要： 随着生物技术和生物医药领域的发展,人们对实验动物的使用需求明显增加,迫切需要开发更具潜力的新型 实验动物资源。棕背䶄和大林姬鼠为野生啮齿动物,二者均为林区害鼠,分布较为广泛。基于目前研究,已大致了 解了棕背䶄和大林姬鼠的生物学特性,推进了棕背䶄和大林姬鼠的实验动物化进程。本文将从遗传学、微生物学、 寄生虫学、行为学和实验动物化5个角度对棕背䶄和大林姬鼠的现有研究内容进行相应概述,为今后实验动物资源的扩展和人类疾病动物模型的构建提供相应理论参考。

关键词: 棕背?, 大林姬鼠, 实验动物资源