Abstract: Objective To investigate the effects of single housing and pair housing on hematological and biochemical parameters, behavior, and immune stress indices of cynomolgus monkeys. Method 3 years old cynomolgus monkeys, 4 males and 4 females, were separated and pair housing by sex. Blood samples were collected at acclimation period, D14 and D21 of single housing and pair housing for hematological, biochemical and immune stress analysis. Behavioral observation was performed during D14 to D21 of single housing and pair housing. Result There was no significant difference in hematological and immune stress indexes of cynomolgus monkeys between single housing and pair housing. In terms of serum biochemistry, compared with the base value, TBIL decreased significantly after pair housing, LDH decreased significantly during single housing. The normal and positive behaviors increased by 27. 93% and 86. 10% respectively, and abnormal behaviors decreased by 26. 31% in cynomolgus monkeys after pair housing. Conclusion The result showed that single housing or pair housing for cynomolgus monkeys had no significant effect on hematological and immune stress indexes. LDH decreased in single housing and TBIL decreased in pair housing, but they were all within the normal background values. The abnormal behaviors of captive cynomolgus monkeys and animal welfare were effectively improved by paired housing.

Key words: cynomolgus monkeys, single housing, group housing, ethology, stress, hematological, biochemical

摘要： 目的 考察食蟹猴单笼和配对饲养对于动物的血液学和血生化、行为学和免疫应激指标的影响。 方法 取 约 3 岁食蟹猴,雌雄各 4 只,分别单笼和同性别配对饲养后,于适应期、单笼饲养第 14 天和第 21 天、配对饲养第 14 天和第 21 天采集动物血样进行血液学、血清生化和免疫应激指标检测;于单笼饲养第 14 ~ 21 天和配对饲养第 14 ~ 21 天进行行为学观察。 结果 单笼和配对饲养食蟹猴的血液学和免疫应激指标均无明显差异;血清生化方面,与 基础值比较食蟹猴配对饲养后的总胆红素( TBIL)有显著性降低,单笼饲养时的乳酸脱氢酶( LDH) 降低明显;配对 饲养后食蟹猴的正常行为和积极行为分别增加了 27. 93% 和 86. 10%,异常行为减少 26. 31%。 结论 单笼饲养和 配对饲养对食蟹猴的血液学及免疫应激指标无明显影响;单笼饲养时动物 LDH 降低,配对饲养时动物 TBIL 降低, 但均在正常背景值范围内;配对的饲养方式能有效改善食蟹猴的异常行为,提高动物福利。 

关键词: 食蟹猴, 单笼饲养, 配对饲养, 行为学, 应激, 血液学, 生化