关键词: 速眠新Ⅱ, 速眠新Ⅱ与戊巴比妥钠联用, 实验用白香猪, 麻醉

Abstract: Objective To observe the anesthetic effect of Su Mian Xin Ⅱ on experimental white miniature pigs.Methods30 adult white miniature pigs were randomly divided into group A,group B,and group C.Simple anaesthesia was performed by intramuscular injection of Su Mian Xin Ⅱ in group A,and combined anaesthesia was performed in group B and group C by intramuscular injections of Su Mian Xin Ⅱ and sodium pentobarbital based on different dosage proportion of the two drugs.The induction period of anaesthesia,maintain duration of anaesthesia,and analepsia period,and temperature,breathing rate,and heart rate during anaesthesia were observed and recorded in the three groups.ResultsIn group A,B,and C,the induction period of anaesthesia was 11.4±7.85 min,5.7±2.51 min,and 4.7±2.83 min respectively,maintain duration of anaesthesia was 122.7±42.82 min,104.4±27.68 min,and 122.8±19.59 min respectively,and analepsia period was 47.8±46.04 min,85.9±92.64,and 102.1±59.62 min respectively.The temperature of all the pigs from the three groups has been trending down from injection of the drug to analepsia.The breathing rate of all the pigs from the three groups has been trending upwards from 10 min to 90 min after injection of the drug,and then was decreased slightly during analepsia period.Heart rate of all the pigs from the three groups was gradually decreased from injection of the drug to analepsia.Conclusion Experimental white miniature pig may possess a stronger toleration to Su Mian Xin Ⅱ,and single application of Su Mian Xin Ⅱ or combined application of it and sodium pentobarbital could achieve more satisfactory anesthesia effect.

Key words: Su-Mian-Xin Ⅱ, Application of Su-Mian-XinⅡ comoounded with sodium pentobarbital, Experimental miniature pigs, Anesthesia