实验动物科学

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室温对家兔体温的影响

任珺;徐文瑜;杜颖;贺争鸣;邢瑞昌;   

  1. 中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所 北京100050,北京100050,北京100050,北京100050,北京100050
  • 收稿日期:2007-04-28 修回日期:2007-04-28 出版日期:2007-04-28 发布日期:2007-04-28

An Observation on the Effect of Room Temperature on the Rabbit's Temperature

REN Jun,XU Wen-yu,DU Ying,HE Zheng-ming,XING Rui-chang   

  1. (National Institute of the Control of Pharmaceutical and Biological Products,Beijing 100050,China
  • Received:2007-04-28 Revised:2007-04-28 Online:2007-04-28 Published:2007-04-28

摘要: 目的分析不同室温对家兔体温的影响。方法根据2000版《中国生物制品规程》热原实验规程对家兔体温进行测定。结果在一定范围内,随着室温的升高,家兔体温筛选合格率也随之升高,在20℃~21℃时家兔体温筛选合格率最低(43%),而在24℃~25℃时筛选合格率最高(71%);室温在22℃~25℃时,家兔体温在38.5℃~39.0℃这一组构成比均超50%。结论不同室温对家兔体温的变化有影响,在进行热原实验前的家兔筛选时应予以注意。

关键词: 室温, 家兔, 体温

Abstract: Objective To observe and analyse the effects of varied room temperature on the rabbit's body temperature.Methods The body temperatures of rabbits were taken according to the pyrogen test norm described in "Requirement for Biologicals of People's Republic of China(2000 Edition)".Results Within the certain range of room temperature,the passing ratio of the rabbit's temperature screening was increasing along with heightening of the room temperature.The passing ratio of the rabbit's temperature screening was the lowest(43%) at 20℃~21℃,while it was the highest(71%) at 24℃~25℃.At 22℃~25℃,the body temperature of more than 50% rabbits was at 38.5℃~39.0℃.Conclusion The change in room temperature could exert an effect on rabbit's temperature.Thus screening of rabbits should be performed according to their temperature before the pyrogen test.

Key words: Room temperature, Rabbit, Body temperature