关键词: 猪圆环病毒, 遗传进化树, 同源性比较

Abstract: In order to know the heredity disciplinarian of porcine circovirus(pcv) and pave the basement for preventing and controlling the disease.In this research,nucleotide sequences of 26 strains of PCV1 and 262 strains of PCV2 were analyzed,also,the ORF1's and ORF2's nucleotide sequences and deduced amino acid sequences were analyzed.At the nucleotide level,the results show that PCV1sequences and PCV2 sequences were divided into two different branches,and among the PCV1 sequences there were no obvious regularity,but among PCV2 sequences,there were divided into two different sub-gene types.The sub-gene typeⅠwas mainly consisted of sequences from American,Canada and Australia,and the sub-gene typeⅡwas mainly consisted of sequences from Franch and Newzealand.At the amino acid level,the phylogenetic tree was very complexity,and there were no obvious regularity.It was found statistically that,although nearly ten years pasted, the sequences homology of PCV had no large changes,the results showed that PCV was very conserved.After analyzed the phylogenetic tree,we discovered that the distributing of PCV had no geographic and time restriction.Also,we analyzed the mutant dots of the PCV2 nucleotide sequences and deduced amino acid sequences,we discovered that,PCV2 nucleotide sequences were easy to has base transversion.

Key words: Porcine circovirus, Phylogenetic tree, Compared of sequences homology