关键词: 情绪应激, 颞下颌关节

Abstract: Objective To study the influence of emotional stress to the ultrastructures of temporomandibular Disorder in rats,and to establish the TMD animal model.Methods 16 male Wistar rats were dividing into 2 groups randomly,one was of which experimental group,and the other was control group.The experimental group was subjected to make chronic unpredictable stress animal model.After 6 weeks,all of rats were killed and their condyles and articular discs were dissected and taken out completely,observing by scanning electron microscope.Result In experimental group,the ethology of rats changed significantly and under scanning electron microscope,the condyles in experimental group were found to have the surface gelatum cracked,disordered and broken collagen fibrils,and exposed deep layer collagen fibrils.The articular discs' surface gelatum were still integrated,but the gyri dispose were irregular.In control group,there were no such changes in condyles and articular discs.Conclusion The chronic unpredictable stress can induce the ultrastructural injuries of temporomandinbular joint in rats,which is consistent with the pathological changes of TMD,so we presumed it is feasible to induce the animal model of TMD.

Key words: Emotional stress, Temporomandibular, Animal model