实验动物科学 ›› 2020, Vol. 37 ›› Issue (04): 78-.

• 研究进展 • 上一篇    

小型猪糖尿病模型研究进展

  

  1. 解放军总医院实验动物中心,北京 100853
  • 出版日期:2020-08-28 发布日期:2020-10-27

Swine Models of Diabetes Mellitus

  • Online:2020-08-28 Published:2020-10-27

摘要: 猪的代谢机制与人类十分相似,是糖尿病研究的理想模型动物。 本文综述了小型猪糖尿病模型的研究进展, 包括 1 型糖尿病模型、2 型糖尿病模型、遗传修饰猪糖尿病模型和糖尿病易感猪。

关键词: 小型猪, 糖尿病动, 物模型

Abstract: Pigs are ideal animals for diabetes mellitus ( DM) research for its similarities with human beings on metabolism. The article reviewed the swine models of diabetes mellitus, which focuses on diagnosis of swine diabetes mellitus, type 1 DM, type 2 DM, genetic modified swine for DM and the nature strains / stocks susceptible to DM.

Key words: minipig, Diabetes mellitus, animal model