关键词: 白血病, 小鼠, 动物模型, 建立方法

Abstract: Mice is an idealmodel animal for leukemia research， which provides important reference function to the leukemogenesis， the development law， the optimization of treatment and the judging prognosis.And it can also make human avoid the huge risk of human trials，being one of the effective tools in basic research.After researchers'ongoing efforts and constant innovation and optimization of establishment method，the biological properties ofm ice model has been closer to clinic and reproduced the relevant performance of clinical leukem ia，which has laid a foundation for leukemia research.This paper mainly summarizes the establishment method，research progress and identification method of leukem ia m ice model in recent years.

Key words: Leukemia, mice, animalmodel, establishmentmethods