关键词: <, p>, 实验动物, 健康监测, 监测方法, 病原<, /p>

Abstract: Abstract: To ensure the repeatability and credibility of the research data，it’s important to investigate the health status of experiment animal which plays a crucial role of human life science research． Depending on many documents and combining with the lab work experience in assessing the quality of laboratory animals for many years，we summarized some recommendations for the monitoring samples and method ． After years of work，we find out that even without obvious clinical features or being diagnosed as microbiological ( virus，bacteria，fungi，and mycoplasmas) and parasitological healthy，the laboratory animals can still have different degrees of pathological damage． These result further demonstrate that there is still a part of them in sub-health status． In conclusion，it’s essential to establish and implement a laboratory animal health monitoring program．

Key words: <p>laboratory animals, health monitoring, monitoring methods, agents</p>