关键词: <, p>, 侧脑室注射STZ, 肠梗阻, 大黄灌胃<, /p>

Abstract: Abstract: Objective To study the therapeutic effects of rats with intestinal obstruction induced by intraventricular injection of STZ in order to improve postoperative survival rate． Method STZ were given intraventricular injection to 60 rats and one week after injection 10 rats with intestinal obstruction were selected for evaluation of therapeutic effects of glycerine enema and radix et rhizoma Ｒhei water，at the same time the rates were supplied with soft food．Then the therapeutic effect was evaluated by the following parameters: food intake，fur color，mental health，emotional reactions，body temperature，stool and urine． Ｒesult During the therapeutic period 2 rats survived and 8 died ( autopsy results revealed the intermediate obstruction，usually with intestinal flatulence，perforation， necrosis． Conclusion The combined therapy with Chinese and Western medicine is simple and relatively successful ( especially the treatment started within 3—5 days after onset) ．

Key words: <p>Intraventricular injection STZ, Intestinal obstruction, Ｒadix et rhizoma Ｒhei</p>