关键词: 精神障碍, 实验动物, 疾病, 模型

Abstract: Abstract: Development of science and technology is dependent on animal model studies，so reliable animal models for various diseases have been developed around the world． And animal models have made a great contribution to the development of modern medicine． However，there are still many difficulties to reproduce human diseases in animals by artificial induction，and clinical signs of many diseases can’t be monitored in laboratory animals or only observed in the higher mammals． Therefore，animal selection and establishment of animal model are important for a successful experimental design and achieving its aim．

Key words: mental disorders, laboratory animals, disease, model