关键词: 苗药, 半截烂, 毒性, 肝, 肾

Abstract: Abstract: Objective Discussion on the Miao medicine( Arisaema rhizomatum) half bad impact on the liver and kidney histology and function in mice，and discussion an the toxicity of thie Miao medicine on liver and kidney in mice． Method Observing the function and pathological changes of liver and kidney by given some dry and fresh Arisaema rhizomatum on mice，which were used respectively to one-off delivery seven days and continuous dosing for thirty days． Ｒesult There was no effect on kidney morphology changes of acute toxicity experiments of Arisaema rhizomatum in mice，but liver cell edema，fresh group was more severity than dry group compared with control group，subacute toxicity experiments show that the levels of ALT，AST and Urea were no significant difference of dose group，but the level of Scr was rose，and dry group has significant difference( P ＜ 0. 05) ，fresh group has extremely significant difference ( P ＜ 0. 01) ． Conclusion There has a certain impact of liver morphology with using Arisaema rhizomatum in mice continuous，but there has no damage to its function; no effect on morphology of renal，but has a certain damage on its function

Key words: : Miao medicine, Arisaema rhizomatum, toxicity, liver;kidney