实验动物科学 ›› 2014, Vol. 31 ›› Issue (03): 60-65.

• 研究 论著 • 上一篇    

大小鼠微卫星和 SNP 遗传检测的研究进展

  

  1. (北京维通利华实验动物技术有限公司,北京 100107)
  • 出版日期:2014-06-29 发布日期:2016-12-05
  • 基金资助:

    北京市科技计划课题《实验动物微生物及遗传检测体系的建立》课题资助( No. 111100067311001)

Advances of Microsatellite and Single Nucleotide Polymorphism Analysis for Genetic Monitoring in Mouse and Rat

  • Online:2014-06-29 Published:2016-12-05

摘要: 摘要: 随着分子生物学技术的迅速发展,微卫星与单核苷酸多态性( single nucleotide polymorphism,SNP ) 技术已成 为实验动物遗传检测的重要手段。微卫星与 SNP 作为一类新型的分子标记,相对于生化与免疫标记,具有快速和 准确等优点。本文就微卫星与 SNP 在大鼠、小鼠遗传检测方面应用的进展做一综述。

关键词: 大鼠, 小鼠, SNP, 微卫星, 遗传检测

Abstract: Abstract: With the rapidly advances in molecular biology technology,microsatellite and SNP has become an important means of analysis for genetic monitoring of laboratory animals. Microsatellite and SNPS,as a kind of new molecular markers,has the accurate and fast advantages,compared with the biochemical and immune markers. In this paper,we will have a detailed development of microsatellite and SNP analysis for genetic monitoring of mouse and rat has been reviewed.

Key words: mouse, rat, microsatellite, SNP, genetic monitoring

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