关键词: 北京地区, 实验动物, 质量监测, 抽检

Abstract: Abstract:Objective To provide reference for production, management and detection of laboratory animal by analyzing of the recently 5 years' test results(2009 - 2013) on microbes, parasites and genetics of laboratory animals in Beijing area. Method According to national and local standard and relevant law and regulation, Beijing Administration Office of Laboratory Animal delegates testing agency to give random tests for qualified laboratory animal manufacturers. Testing reports could be provided by testing agency. And according to the 5 - year data from the reports, we can analyze the quality of different kinds of laboratory animal (including mice, rats, guineas, rabbits, dogs, monkeys and miniature pigs) in Beijing area. Result The quantity and batches of random testing laboratory increased by years, while the qualified rate of batches turned to be declined. Laboratory animals of different grades (SPF, CL, CV) had varying degrees infection, and toxoplasma infection existed in all the 5 years. Immune antibody non-compliance of CV laboratory animal continued to be there, and there are tendency of going up and co-infection. Meanwhile, there were 3 batches of inbred mice failing to pass the genetic monitoring. Conclusion Quality monitoring of laboratory animal is the effective means of animal quality. And it is essential to the development of medicine, life science and technology, and laboratory animal industry.

Key words: Beijing area, laboratory animals, quality monitoring, random testing