Abstract: Abstract: Objective To investigate the occurrence and pathological characteristics of canine epidermal tumors, the background information and pathological diagnosis result of 39 cases of canine epidermal tumor were analyzed.Method Thirty nine cases of canine epidermal tumors were collected and sectioned for HE staining. Pathological observation and diagnosis were made by light microscope. According to the diagnosis result , the information of tumor types, ages, sexes and sites of the lesion were statistically analyzed. Result The statistical results show that the most common epidermal tumor in canine is squamous cell carcinoma, accounting for 46% of all cases of epidermal tumors, most of which are moderately differentiated squamous cell carcinoma. The second is papillomas with the proportion of 39%, mainly exophytic papillomas. Basal squamous cell carcinoma is rare. Papillomas are more common in 0-3-year-old dogs, squamous cell carcinoma and basal squamous cell carcinoma are more common in dogs over 7 years old. The incidence of male was slightly higher than that of female. In canine, the epidermal tumor most frequently occurs on the head. Conclusion The histological features and epidemic characteristics of canine epidermal tumors are summarized, which provides a reference for the diagnosis and differential diagnosis of this kind of tumors.