关键词: <, p>, SPF 级FMMU 白化豚鼠, 血液指标, 颈总动脉压, 心室压, 脏器参数<, /p>

Abstract: Abstract: Objective To determine and compare the basic parameters of blood，heart rate，carotid artery pressure，ventricular pressure and organ parameters of SPF( specific pathogen free) FMMU albino guinea-pig． Method The heart blood was collected and blood physiological and biochemical index were measured in a total of 30 SPF FMMU albino guinea-pigs of about 250—300 g weight，and blood gas was determined． Blood pressure in carotid artery was measured by arterial puncture． Ventricular pressure and heart rate were measured on the respiratory support condition． Ｒesult The differences of ＲBC、HGB、HCT、AST、AMY、CHOI、TCO2、HCO －3 、THbc、Na + in male and female SPF FMMU albino guinea-pig were significant( P ＜ 0. 05 or P ＜ 0. 01) ． The differences of carotid diastolic blood pressure and mean arterial pressure，left ventricular diastolic pressure，right ventricular systolic pressure and mean pressure were also significant ( P ＜ 0. 05 or P ＜ 0. 01) ． Finally，differences in both body weight and brain weight，and organ coefficient of pituitary，adrenal gland and left /right kidney were significantly different ( P ＜ 0. 05 or P ＜ 0. 01) ． Conclusion There were differences of blood physiology and biochemistry，blood gas，carotid artery pressure，ventricular pressure and organ parameter in different gender of the SPF FMMU albino guinea-pig．

Key words: <p>SPF FMMU albino guinea-pig, blood parameter, carotid artery pressure, ventricular pressure, organ parameter</p>