关键词: SPF, 大鼠和小鼠, 生长曲线, Bertanlanffy 模型

Abstract: Abstract: Analysis and fitting of the growth curve was important when the regular pattern of growth and development was studied． The growth curve of 960 rats and mice of six species was analyzed with the help of the Bertanlanffy model． The results showed that Bertanlanffy model was more suitable for simulating animal growth( R2 ＞ 0. 948) ．The relative growth rate and the absolute growth rate of mice were in decline，and the relative growth rate of rats showed a downward trend，while the absolute growth rate reached a peak after the decline． Bertanlanffy model has been widely used in research for prediction of growth rate and genetic analysis of growth process，and can also provide the basic data for the standardization of laboratory animals．

Key words: SPF, rats and mice, growth curve, Bertanlanffy model