关键词: 小型猪, 2 型糖尿病, 巴马小型猪, 遗传选育

Abstract: Abstract: Minipigs are ideal animals for diabetes mellitus ( DM) research for its similarities with human beings on metabolism． However，during the long-term selection as domestic animals，pigs have developed the features resisted to suffer from DM． We have screened 245 boars and sows of Bama minipigs with fasting blood glucose ( FBG) ，and a high FBG pregnant pig was found． 11 piglets ( 10 survived) were born from the pig and as founders to selecting breeding． After 2 generations selection with susceptibilities to diet-induced type 2 DM，the inducing period from 7 months shortened to 6 months． It is speculated that a new line of Bama minipgs susceptible to dietinduced DM will be developed in the future．

Key words: minipig, type 2 diabetes mellitus, Bama minipig, genetic selection