实验动物科学 ›› 2010, Vol. 27 ›› Issue (05): 34-37.

• 研究 论著 • 上一篇    下一篇

复方红花降压胶囊的降脂作用及安全性动物实验研究

  

  1. 1.吉林大学白求恩医学院动物实验中心,长春130021
    2.吉林大学体育学院运动人体实验中心,长春130012
  • 出版日期:2010-11-05 发布日期:2013-05-22

Lipid-lowering Effect and Safety Assessment of the Compound Safflower Buck Capsule in Laboratory Rats

  • Online:2010-11-05 Published:2013-05-22

摘要: 摘要:目的观察复方红花降压胶囊对高血脂大鼠的治疗效果及其毒性。方法通过对Wistar大鼠饲喂高脂料。 导致实验用大鼠产生高血脂模型。对模型动物采用复方红花降压胶囊灌胃治疗。结果复方红花降压胶囊对高 血脂大鼠具有降血脂作用,其降脂作用显著。并对机体体无毒性作用。结论复方红花降压胶囊对高血脂大鼠有明 显降脂作用,为应用于临床治疗高血压提供了理论依据。

关键词: 复方红花降压胶囊, 大鼠, 高脂料

Abstract: Abstract: Objective To investigate the lipid—lowering effect of the compound safflower buck capsule in hyperlipidemia rats and its toxicity.Methods Hyperlipidemia rat model was established by high—fat feeding,and then administration of compound safflower capsules was performed by oral gavage.Results and Conclusion The compound safflower buck capsule has a significant lipid—lowering effect on hyperlipidemia rats with no toxicity, which provides an experimental basis for clinic application of the compound safflower buck capsule in hyperlipidemia therapy.

Key words: Compound safflower buck, Rats, High-fat feeding