关键词: 强心颗粒, 活血化瘀, 微循环障碍, 血液流变学

Abstract: Objective To study the activating blood circulation to dissipate blood stasis effects of Qiangxinkeli(QXKL).Methods Established the mesentery microcirculation disturbance with adrenaline in mice to observe the effect of QXKL on the mesentery microcirculation disturbance;subcutaneous injecting adrenalin hydrochloride twice,during the period,stimulating the rats with the ice water to induce the acute blood stasis model to survey the influence on the hemorheology.Results QXKL low dose 21.5 g /kg、middle dose 43 g /kg and high dose 86 g /kg could accelerate the blood flow rate,improve the blood flow state,thereby ameliorate the microcirculation disturbance in mice;QXKL middle dose 30 g /kg and high dose 60 g /kg could reduced the blood viscosity in high、 midst and low shear rate in model rats remarkably,the high dose could degrade the hematocrit and the midst dose could accelerate the erythrocyte electrophoresis time.Conclusion QXKL possesses the obvious activating blood circulation to dissipate blood stasis effects.

Key words: QXKL, Activating blood circulation to dissipate blood stasis, Microcirculation disturbance, Blood rheology