实验动物科学

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抑郁症动物模型概述及评价

秦琴;刘利学;   

  1. 成都医学院药学院药学实验中心;
  • 收稿日期:2010-02-28 修回日期:2010-02-28 出版日期:2010-02-28 发布日期:2010-02-28

Review of Animal Models for Depression

QIN Qin, LIU Li-xue   

  1. (Pharmaceutical Laboratory Center, Pharmaceutical College of Chendu Medical College, Chengdu 610081, China
  • Received:2010-02-28 Revised:2010-02-28 Online:2010-02-28 Published:2010-02-28

摘要: 疾病研究和新药开发依赖于有效的实验性动物模型的建立和应用。该文阐述了目前在药理学研究中常用的几类抑郁症动物模型,并对模型建立的原理及其应用作了介绍,对未来发展抑郁症动物模型提出了一些设想。

关键词: 抑郁症, 动物模型, 评价

Abstract: Commonly used animal models of depression in the pharmacological studies are reviewed, and their application and mechanism are also described. Development of the further models of depression is proposed simultaneously.

Key words: Depression, Animal model