关键词: 猕猴, 妊娠异常, 弓形虫

Abstract: Objective To investigate the cause of unusual pregnancy in rhesus macaques breeding colony.Methods Several factors relating to unusual pregnancy,such as infective pathogens(toxoplasma,Tox),environmental elements and other factors with the similar physiology and biological character in human,were analyzed.In this study,29 samples were collected from unusual pregnancy cases and Toxoplasma gondii DNA extracted from blood was examined,using normal delivery group and normal adult macaque group as controls.Results Statistical results showed that toxoplasma infective rate of the unusual pregnancy samples were 34.4%,significantly higher than those of the normal delivery group(12.5%,P<0.05) and the normal adult macaque group(5.0%,P<0.05).The unusual pregnancy rates were significantly different among macaques housed in distinct environments.Conclusion Toxoplasma infection,environment,maternal age and parity,are the factors relating to unusual pregnancy of rhesus macaques,which will be decreased according to our proposed measures.

Key words: Rhesus macaque, Unusual pregnancy, Toxoplasma gondii, Environment