关键词: 氯胺酮, 速眠新Ⅱ, 食蟹猴

Abstract: Objective To observe the anesthetic effect of ketamine in combination with sumianxin II on cynomolgus monkey.Methods One hundred and fifty-four cynomolgus monkeys were anesthetized using sumianxin Ⅱ(0.1 mL/kg,im) and ketamine(0.1 mL/kg,im) for renal transplantation,and maintenance of anesthetic and analgesic effects,breathing frequency(BR),heart rate(HR),and resuscitation time after operation,were monitored.Results All the monkeys survived,and none of them died of anesthesia;the maintained anesthetic time was 50～70 mins after first administration.During operation,the BR and HR were(40～55)/mins and(60～74)/mins respectively.All the cynomolgus monkeys waked up in(25～35) mins after operation.Conclusions It is a good anesthesia method to use ketamine in combination with sumianxin Ⅱ,and the does is reduced considerably.The cynomolgus monkeys waked up soon after operation.The muscle is well relaxed,and BR and HR are kept stable during anesthesia.It is an excellent and safe method to anesthetize cynomolgus monkey that using ketmine in combination with sumianxin Ⅱ.

Key words: Ketamine, Sumianxin Ⅱ, Cynomolgus monkey, Anesthesia