关键词: 珍田胶囊, 长期毒性, 血液学指标, 血生化

Abstract: Objective To explore the influences of ZhenTian capsule on blood cell composition, liver function, and kidney function. Methods The rats were orally given ZhenTian capsule for 180 days with the doses of 1.315,2.63 and 5.26g(crude medicinal materials)/kg(13,26.1 and 52.2 times of clinic does) while the control group was given the distilled water of the same volume and for 4 weeks of stopping administration. Meanwhile, rats' behavior and appearance were observed, and night shit and urine everyday amounts were measured. The rat's indexes of hematology and biochemistry were determined. Results All the detected indexes were in normal rang. The value of blood routine and biochemical indices in the tested group had no difference compared with controlled group. Conclusion Taking long-time ZhenTian capsule has no a bad influence on blood composition,liver and kidney functions.

Key words: ZhenTian capsule, Long-term toxicity, Index of hematology