关键词: 龙肽免疫胶囊, 急性毒性, 微核, 精子畸形

Abstract: Objective To test the safety of Long-tai capsule as functional food.Methods Acute toxicity test,Bone marrow cell micronucleus test,Mice sperm abnormality test and 30 days feeding test were selected to study the toxicity of Long-tai capsule.Results In acute toxicity test,male and female KM mice were given with 20g/kg dose of Long-tai capsule two times within 24h,no toxic symptom were observed and no death.The results of bone marrow cell micronucleus test,mice sperm abnormality test were negative.In the 30 days feeding test,compared with control group,1.25%、2.50% and 5.00% contents of Long-tai capsule in the feed(as 25、50、100 times of population recommended amount respectively)showed no obvious toxic effects in clinical examination,blood test,biochemical test,organisms weight and pathological observation to Wistar rats.Conclusion Long-tai capsule is safe as a kind of functional food.

Key words: Long-tai capsule, Acute toxicity, Micronucleus, Sperm abonormality