实验动物科学

• 论文 • 上一篇    下一篇

戊巴比妥钠在实验动物兔麻醉中的应用分析

彭长凌;朱裕华;朱孝荣;   

  1. 徐州医学院实验动物中心,徐州医学院实验动物中心,徐州医学院实验动物中心 徐州221002,徐州221002,徐州221002
  • 收稿日期:2006-03-25 修回日期:2006-03-25 出版日期:2006-03-25 发布日期:2006-03-25

Analysis of Application of Pentobarbital Sodium to Anesthesia of Laboratory Rabbits

PENG Chang-ling,ZHU Yu-hua,ZHU Xiao-rong   

  1. (Laboratory Animal Center of Xuzhou Medicine College,Xuzhou 221002,China
  • Received:2006-03-25 Revised:2006-03-25 Online:2006-03-25 Published:2006-03-25

摘要: 目的比较分析各麻醉方式的麻醉效果。方法采用静脉、肌肉、腹腔和皮下四种方式注射3%戊巴比妥钠,分别以30mg/kg、30mg/kg、30mg/kg、40mg/kg的剂量对兔施行麻醉,记录实验中每只动物的麻醉时间、睡眠时间、麻醉后睫毛反射、刺痛反应、体温、呼吸频率及苏醒后恢复时间等,统计所得数据。结果用确定剂量,各麻醉方式的麻醉时间为0~17min,睡眠时间范围为46~89min,恢复时间范围为26~41min。结论实验者在实验时可根据需要用所确定剂量选择不同麻醉方式对实验动物兔施行麻醉。

关键词: 麻醉, 戊巴比妥钠

Abstract: Objective To compare the effect of pentobarbital sodium injected in several ways.Method Rabbits were injected with 3% pentobarbital sodium intravenously,intramuscularly,peritoneally and subcutaneously.And the dose of each method was 30 mg/kg,30 mg/kg,30 mg/kg and 40 mg/kg.Time of anesthetizing and sleeping were recorded and also eyelash reflex,reaction of stion,body temperature,breathing frequency,and the time of recover after being anesthetized were recorded.The experiment data were collected.Results The range of anesthetizing time,sleeping time and recover time were 0~17 minutes,46~89 minutes and 26~41 minutes,respectively.Conclusion Researchers may choose different method to anesthetize laboratory rabbits with the dose given in the article.

Key words: Anesthetize, Pentobarbital sodium