关键词: 突变小鼠, 血液学, 血液生化指标

Abstract: Mutant hairless mice with a first sparse coat appeared spontaneously in the production stock of normal BALB/c mice. For study of mutant hairless gene affected biological characteristics of the mice,hematological and blood biochemical index of F 2 mutant hairless mice were determined. The results showed there were a few significant differences in mice between sexes (male and female mice).There were significant differences Bun,Ca of mutant hairless mice.There were significant differences WBC,RBC,HCT,GPT.Alb,Mg of sparse-haired mice. The results showed there were significant differences between metabolize and electrolyte of F 2 mutant hairless mice and mutant hairless gene affected the metabolize infection.

Key words: Mutant hairless mice, Hematological parameters, Biochemical parameters