实验动物科学

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两种不同品系小鼠血清TC和TG值的比较

陈嘉,邹移海,张薇,苏小茹,符路娣   

  1. 广州中医药大学实验动物中心,广州中医药大学实验动物中心,广州中医药大学实验动物中心,广州中医药大学实验动物中心,广州中医药大学实验动物中心 广州510405 ,广州510405 ,广州510405 ,广州510405 ,广州510405
  • 收稿日期:2003-12-25 修回日期:2003-12-25 出版日期:2003-12-25 发布日期:2003-12-25

The Comparison of Total Cholesterol and Triglyceride Between Two Strains of Mice

CHEN Jia,ZOU Yi hai,ZHANG Wei,SU Xiao ru,FU Lu di   

  1. (Laboratory Animal Center,Guangzhou University of Traditional Chinese Medicine,Guangzhou\ 510405
  • Received:2003-12-25 Revised:2003-12-25 Online:2003-12-25 Published:2003-12-25

摘要: 目的 检测SPF级KM和NHI小鼠血清总胆固醇 (TC)和甘油三酯 (TG)值。方法 TC测定采用酶法 (终点法 CHO PAPMethod) ,TG测定采用酶法 (终点法 GPO PAPMethod)。结果  (1)雌性KM小鼠血清TC和TG值分别为(2 5 5± 0 4 5 )mmol L和 (0 96± 0 2 0 )mmol L ;(2 )雄性KM小鼠血清TC和TG值分别 (2 80± 0 4 5 )mmol L和 (0 78±0 17)mmol L ;(3)雌性NIH小鼠血清TC和TG值分别 (3 74± 0 5 6 )mmol L和 (2 19± 0 81)mmol L ;(4 )雄性NIH小鼠血清TC和TG值分别为 (4 2 3± 0 77)mmol L和 (1 4 4± 0 5 5 )mmol L。结论 不同性别、不同品系的小鼠间的血清TC、TG值差异均有统计学意义 ,性别及品系对小鼠血清TC、TG值有影响

关键词: 动物实验, 血脂, 甘油三酯

Abstract: Objective\ To compare the Concertritions of total Cholesterol(TC) and Triglyceride(TG) in the KM and NIH mouse of SPF.Method\ CHO PAP Method was used to determine TC;GPO PAP Method was used to determine TG.Result\ (1)The result of the female KM mouse was TC:(2 55±0 45)mmol/L,TG:(0 96±0 20)mmol/L.(2)The result of the male KM mouse was.TC:(2 80±0.45)mmol/L,TG:(0 78±0 17)mmol/L.(3)The result of the female NIH mouse was TC:(3 74±0 56)mmol/L,TG:(2 19±0 81)mmol/L.(4)The result of the male NIH mouse was TC:(4 23±0 77)mmol/L,TG:(1 44±0 55)mmol/L.Conclusion\ Sex and strain could affect on TC and TG of mice.

Key words: Animal experiment, Blood fatty, Total Cholesterol, Triglyceride