用鼠耳肿胀法研究抗炎药实验方法的改进

实验动物科学

用鼠耳肿胀法研究抗炎药实验方法的改进

郭淑芳,杨彤

大连铁路卫生学校药理教研室,大连医科大学药理教研室大连116001 ,大连116027

收稿日期:2003-09-25 修回日期:2003-09-25 出版日期:2003-09-25 发布日期:2003-09-25

Modification of Ear-swelling Model in Mouse

GUO Shu fang 1, YANG Tong 2

(1.Nailway Health School of Dalian, Dalian\ 116001)(2.Dalian Medical University, Dalian\ 116027

Received:2003-09-25 Revised:2003-09-25 Online:2003-09-25 Published:2003-09-25

摘要/Abstract

摘要： 鼠耳肿胀法是常用的抗炎药的筛选实验方法。致炎剂的涂布是个十分关键的步骤 ,对于初学者来说 ,很难在短时间内迅速掌握技巧 ,从而很好地开展实验。快速在鼠耳前后表面中央定点推注致炎剂 ,利用其自然扩展浸润现象致炎 ,方便快捷 ,准确度大大提高 ,对于初学者来说十分适用

关键词: 抗炎药实验, 鼠耳肿胀法, 致炎剂

Abstract: Ear swelling model is commonly used in the study of anti inflammatic assay. The method of coating inflamma tic agent on mice's ears is the key step during experiment. Dropping the inflammatic agent on the ear's central section is more effective than daubing it on the whole ear. The comparison is done via experiments of the same person.

Key words: Anti inflammatic experiment, Ear swelling model, Inflammatic agent, Inunction

郭淑芳,杨彤. 用鼠耳肿胀法研究抗炎药实验方法的改进[J]. 实验动物科学.

GUO Shu fang 1, YANG Tong 2. Modification of Ear-swelling Model in Mouse[J]. laboratory animal science.