实验动物科学 ›› 2024, Vol. 41 ›› Issue (5): 9-12.DOI: 10.3969/j.issn.1006-6179.2024.05.002

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SPF 级封闭群长爪沙鼠生长发育及繁殖性能研究

  

  1. (首都医科大学实验动物部,北京 100069)
  • 收稿日期:2023-09-01 出版日期:2024-10-28 发布日期:2024-10-28
  • 作者简介:乔彦华( 1982—) ,女,主管技师,负责实验动物相关技术服务,E-mail:jasmine422@ ccmu. edu. cn。
  • 基金资助:
    国家重点研发计划( 2021YFF0702805)

Study on Growth and Reproductive Performance of SPF Closed Colony Mongolian Gerbi#br#

  1. (Department of Experimental Animals, Capital Medical University, Beijing 100069,China)
  • Received:2023-09-01 Online:2024-10-28 Published:2024-10-28
  • Contact: 卢 静( 1969—) ,女,教授,研究方向为实验动物管理及比较医学研究,E-mail:lujing@ ccmu. edu. cn。

摘要:

目的 了解 SPF 级封闭群长爪沙鼠的生长发育及繁殖性能,进一步完善其生物学特性,为长爪沙鼠标准化研
究及相关科研工作提供数据参考。 方法 从饲养在屏障环境中的 SPF 级封闭群长爪沙鼠群体中随机挑选 44 对繁
殖性能良好的长爪沙鼠进行配种,记录并统计相关繁殖信息。 随机挑选出生后的长爪沙鼠 80 只( 雌雄各半) ,定期
称重并绘制 1 ~ 77 日龄生长曲线。 结果 长爪沙鼠窝产仔数主要分布在 4 ~ 9 只,占总胎数的 84. 2%。 胎间隔主要
分布在 24 ~ 35 d,占总胎数的 72. 1%。 初产日龄主要分布在 82 ~ 134 d,占总雌鼠量的 77%。 离乳率为 100%的胎数
占总胎数的 79%。 结论 屏障环境中饲养的 SPF 级封闭群长爪沙鼠繁殖性能良好,母性良好且产后即可交配受
孕。 长爪沙鼠最适离乳日龄为 25 日龄。 25 ~ 42 日龄长爪沙鼠体质量增长最快。 42 ~ 77 日龄雄性长爪沙鼠体质量
显著大于雌性。

关键词:

Abstract:

Objective
To explore the growth, development and reproductive performance of SPF closed
colony Mongolian gerbil, further improve its biological characteristics, and provide data reference for the
standardization research and related scientific research of Mongolian gerbil. Method
Forty four pairs of
Mongolian gerbil with good reproductive performance were randomly selected from the SPF closed colony
of Mongolian gerbil raised in a barrier environment for breeding, and the relevant reproductive information
was recorded and counted. Eighty Mongolian gerbil ( half male and half female) were randomly selected
after birth, weighed regularly and drew a 1 - 77 day growth curve. Result
The litter size of Mongolian
gerbil was mainly distributed between 4 - 9, accounting for 84. 2% of total number of fetuses. The
gestational interval is mainly distributed between 24 and 35 days, accounting for 72. 1% of the total
number of fetuses. The initial production age is mainly distributed between 82 and 134 days, accounting
for 77% of total number of female Mongolian gerbils. The number of fetuses with a 100% weaning rate
accounts for 79% of the total number of fetuses. Conclusion
The SPF closed colony Mongolian gerbil
raised in the barrier environment has good reproductive performance, good maternity and can mate and

conceive after delivery. The optimal weaning age of Mongolian gerbil was 25 days. At 25-42 days old,

Mongolian gerbil gained the fastest weight. At the age of 42 to 77 days, the weight of males is
significantly greater than that of females.

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