关键词: 升压物质检查法, 升压素, 血压, 生物安全性检查

Abstract: The vasopressor activity test is one of the drug biological safety test method included in theChinese Pharmacopoeia. It is used to detect whether the limits of vasopressor in APIs and relatedpreparations that may contain impurities which may raise blood pressure meet the standard requirements.Although the application of this test is narrow, it plays an important role in the safety of clinicaltreatment. This article summarizes the experimental principles, experimental systems, methodapplications, improvement suggestions, and experimental key points of the vasopressor activity test, sothat provides references for relevant experimenters.

Key words: vasopressor activity test, vasopressin, blood pressure, biological safety tests