关键词: 脊柱关节炎( SpA) , 动物模型, 附着点炎, 炎症

Abstract: Spondyloarthritis ( SpA) is a common autoimmune disease that mostly affects the axial and peripheral joints. It is characterized pathologically by enthesitis, bone breakdown, and new bone formation. The development of an animal model will provide a good platform for in-depth study of the pathogenesis and therapy of SpA, so this article will review the development of SpA animal model research and strive to provide new ideas for the study and establishment of a SpA animal model, which will further enhance the research theory and experimental basis of the SpA animal model, bringing new ideas for the study of the pathogenesis and clinical therapy of SpA. 

Key words: spondyloarthritis ( SpA) , animal model, enthesitis, inflammation