关键词: 恒河猴, 食蟹猴, 白细胞总数, 白细胞分类, SIVmac

Abstract: objective\ To compare and observe the granulocyte series in peripheral blood in SIVmac\|infected Rhesus monkey and Cynomolgus monkey .Method\ Examine the quantity and morphology of the WBC by routine method.Results\ The peripheral blood granulocyte in SIVmac\|infected Rhesus monkey and Cynomolgus monkey ,similar to those seen in human AIDS,showed a regular change on the quantity and morphology of the WBC.3 Rhesus monkeys and 4 Cynomolgus monkeys are incluted in this research.The WBC count started to decrease and abnormal lymphocytes increase two weeks after infected with SIV virus on Rhesus monkey and Cynomolgus monkey ,and then the value of WBC elevated continuously to a peak,abnormal lymphocytes remained increase;8 weeks later,the WBC and abnormal lymphocytes started to decrease,three Cynomolgus monkeys died from viremia in 8 weeks.The WBC decreased continuously in a remaining Cynomolgus monkey in 12 weeks.Conclusion\ This essay showed phenomena of WBC changes is similar to diagnostic criterion of human HIV/AIDS.Besides, Cynomolgus monkey is more sensitivity than Rhesus monkey in SIVmac infection.

Key words: Rhesus monkey, Cynomolgus monkey, WBC, WBC.DC, SIVmac