速眠新Ⅱ对幼龄贵州小型猪外科手术中的应用研究

实验动物科学

速眠新Ⅱ对幼龄贵州小型猪外科手术中的应用研究

吴曙光;佘小明;田锟;赵菊花;巫全胜;郭科男;董小君;钱宁;

贵阳中医学院实验动物研究所,贵阳市口腔医院,贵阳市口腔医院,贵阳中医学院实验动物研究所,贵阳中医学院实验动物研究所,贵阳中医学院实验动物研究所,贵阳中医学院实验动物研究所,贵阳中医学院实验动物研究所贵阳550002,贵阳550002,贵阳550002,贵阳550002,贵阳550002,贵阳550002,贵阳550002,贵阳550002

收稿日期:2006-12-25 修回日期:2006-12-25 出版日期:2006-12-25 发布日期:2006-12-25

Study of Drugs "Su-Mian-Xin Ⅱ" Application on Guizhou Miniature Piglets Under Surgical Operation

WU Shu-guang~1,SHE Xiao-ming~2,TIAN Kun~2,ZHAO Ju-hua~1,WU Quan-sheng~1,GUO Ke-nan~1,DONG Xiao-jun~1,QIAN Ning~1

(1.Laboratory Animal Institute,Guiyang Traditional Chinese Medial College,Guiyang 530002,China)(2.Guiyang Stomalogical,Hospotil,Guiyang 550002,China

Received:2006-12-25 Revised:2006-12-25 Online:2006-12-25 Published:2006-12-25

摘要/Abstract

摘要： 目的研究速眠新Ⅱ在贵州小型猪幼龄猪外科手术中的麻醉效果和应用。方法将30头贵州小型猪幼龄猪分成两组,A组用速眠新Ⅱ0.15 mL/kg肌注麻醉;B组用0.1 mL/kg速眠新Ⅱ与3.5%戊巴比妥钠生理盐水溶液0.5 mL/kg同时肌注麻醉。两组动物均进行腭裂造模术及腭裂修补术、器官切除术、腹腔探察术、清创术等手术。观察两组动物的麻醉诱导期、维持期、苏醒期及动物的体温、呼吸频率、心率变化。结果A、B两组的诱导期分别为(7.67±5.20)min、(3.58±3.20)min;维持期分别为(40.17±4.96)min(、60.50±17.3)min;苏醒期分别为(7.00±2.45)min(、56.27±33.60)min。体温变化:A组先下降,后上升;B组总体持续下降。两组动物呼吸频率和心率平稳。结论速眠新Ⅱ用于幼龄贵州小型猪外科手术中的麻醉、镇痛和镇静及肌松效果良好、与戊巴比妥钠复合麻醉效果良好。

关键词: 速眠新Ⅱ, 贵州小型猪, 幼龄, 外科手术, 麻醉

Abstract: Objective To study the anesthetic effect and application of drugs "Su-Mlian-Xin Ⅱ" on Guizhou miniature piglets under surgical operation.Methods 30 Guizhou miniature piglets were randomly divided into two groups:Group A and Group B.Group A were anesthetized by muscle injection of drugs "Su-Mian-Xin Ⅱ"(0.15mL/kg),while Group B were anesthetized by muscle injection of drugs !Su-Mian-Xin Ⅱ"(0.1 mL/kg) and 3.5% sodium pentobarbital solution(0.5mL/kg) simultaneously.Both groups underwent operations such as cleft palate casting,organ resection,peritoneo-probing and debridement etc.Both groups were observed in respect of stage of anesthesia induction,stage of maintain,and stage of analepsia,in addition,the heat,respiration rate and heart rate variation of piglets.Results Group A and Group B were recorded respectively with stage of anesthesia induction(7.67±5.20)min vs(3.58±3.20) min,stage of maintain (40.17±4.96)min vs(60.50±17.37) min,and stage of analepsia(7.00±2.45) min vs(56.27±33.60)min.As for the heat,a change of going down and then up was shown in Group A while constant drop was shown in Group B as a whole.Respiration rate and heart rate remained stable in both groups. Conclusion Drugs "Su-Mian-Xin Ⅱ" have satisfactory effects on surgical operation for Guizhou miniature piglets pertaining to anesthesia,pain easing,pacifying and muscle relaxing.Drugs Su-Mian-Xin Ⅱ" have good effects on anesthetic effect when compounded with sodium pentobarbital.

Key words: "Su-Mian-Xin Ⅱ", Guizhou Miniature Pigs, Piglets, Surgical Operation, Anesthesia

吴曙光;佘小明;田锟;赵菊花;巫全胜;郭科男;董小君;钱宁;. 速眠新Ⅱ对幼龄贵州小型猪外科手术中的应用研究[J]. 实验动物科学.

WU Shu-guang~1,SHE Xiao-ming~2,TIAN Kun~2,ZHAO Ju-hua~1,WU Quan-sheng~1,GUO Ke-nan~1,DONG Xiao-jun~1,QIAN Ning~1. Study of Drugs "Su-Mian-Xin Ⅱ" Application on Guizhou Miniature Piglets Under Surgical Operation[J]. laboratory animal science.

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