关键词: 肃肺润肠汤, 大鼠, 药物依赖性便秘

Abstract: Objective To evaluate the effects of the Sufeirunchang Decoction on rat drug dependence constipation.Methods 30 Clean level SD rats were divided randomly into the normal control group(n=10),model group(n=10)and treatment group(n=10).Beside the control group,each group by limiting water but limitless diet contributes to cause the constipation.It is repeatedly treated by infusing stomach with rhubarb so as to cause medicine dependent constipation.The normal control group rats are filled the stomach with the distilled water.Treatment group tats are filled stomach with Sufeirunchang Decoction for observing the effect of Sufeirunchang Decoction to this disease model.Observation target:Excrement displacement /unit time,First grain of bowel movement discharges time,Barium sulfate advance rate in small intestine.The article compared the effect of Sufeirunchang Decoction around treatment with above targets.Results(1)each model group is worse than the normal control grouping ordinary circumstances excrement displacement is fewer and the nature is harder;intestinal tract transmission function is slow-down.The difference is significant(P<0.05).(2)The control group rats have not any abnormal performance.(3)The ordinary circumstances of model group rats is good after feeding the medicine;intestinal tract transmission function is close to normal control group;the difference is not significant(P>0.05).Conclusion The Sufeirunchang Decoction may improve the function of gastro-intestinal tract of rats;recover drug dependent constipation and promote stomach and intestines creeping motion.

Key words: The Sufeirunchang Decoction, Rats, Drug dependence constipation