实验动物科学

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实验用斑马鱼主要疾病及其实验动物标准化研究过程面临的主要问题

吴思奡;王箐;高昌;穆苑;赵德明;孙德明;   

  1. 中国农业大学动物医学院;国家人口计生委科研所;
  • 收稿日期:2009-08-28 修回日期:2009-08-28 出版日期:2009-08-28 发布日期:2009-08-28

The Common Diseases and Main Problems for Research of Standardization of the Laboratory Zebrafish

WU Si-ao~1,WANG Qing~1,GAO Chang~2,MU Yuan~2,ZHAO De-ming~1,SUN Deming~2   

  1. (1.China Agricultural University,Beijing 100094,China)(2.National Research Institute for Population and Family Planning,Beijing 10008,China
  • Received:2009-08-28 Revised:2009-08-28 Online:2009-08-28 Published:2009-08-28

摘要: 斑马鱼是目前国际上用于实验研究最广的鱼类,但是鱼类实验动物尚未实现实验动物的标准化,甚至还没有国家或地方统一的技术标准。本研究收集、分析整理了实验用斑马鱼的主要疾病以及培育饲养实验用斑马鱼所面临的生物净化问题的资料及数据,为我国鱼类实验动物标准的制订和标准化鱼种群的建立及其质量控制与评价提供技术依据。

关键词: 斑马鱼, 实验动物, 疾病, 标准化, 生物净化

Abstract: Zebrafish is a kind of fish widely used in laboratories.The standardization of laboratory zebrafish has not been established and there is even no national or regional approved technique standard.The purpose of this review is to collect and analyze the information of the common diseases of zebrafish and the possible problems that may occur in the procedure of biological purification,which will provide the technical basis for formulation of laboratory fish standardization and quality control,and for evaluation of standarlized zebrafish species.

Key words: Zebrafish, Laboratory animal, Disease, Standardization, Biological purification