实验动物科学 ›› 2026, Vol. 43 ›› Issue (4): 79-84.DOI: 10.3969/ j. issn.1006-6179.2026.04.012

• 论著 • 上一篇    下一篇

高温高湿环境对非灭菌性垫料卫生指标的影响

  

  1. (中国药品检定研究院 国家啮齿类实验动物资源库,北京 102629)
  • 收稿日期:2025-10-15 出版日期:2026-08-28 发布日期:2026-09-07
  • 通讯作者: 左 琴(1975—),女,副研究员,研究方向为实验动物遗传与资源保存。E-mail:zuoqin2001@163.com。
  • 作者简介:王学文(1979—),女,高级兽医师,研究方向为实验动物兽医与质量管理。E-mail:wangxuewen320@163.com。

Impact of High Temperature and High Humidity Environment on the Hygienic Indicators of Non-Sterilized Bedding

  1. (National Rodent Laboratory Animal Resources Center,National Institutes for Drug Control, Beijing 102629,China)
  • Received:2025-10-15 Online:2026-08-28 Published:2026-09-07

摘要: 目的 探究高温高湿环境中不同储存时长对非灭菌性杨木刨花垫料卫生指标(微生物指标和化学污染物指 标)的影响,为垫料储存过程中的温湿度调控及质量管控提供科学数据支撑。方法 将非灭菌杨木刨花垫料随机 分为A组、B组和C组,分别在0、7、14、21及28 d进行样品采集,检测其微生物及化学污染物指标。结果 3组储 存环境的温湿度存在显著差异;在0至28 d的储存周期内,3组垫料的霉菌与酵母菌指标均未达到合格标准;14 d 时,A组和B组的大肠埃希菌指标不合格;21 d及28 d时,3组大肠埃希菌指标均处于不合格状态。结论 高温高 湿环境会对非灭菌性垫料微生物指标产生显著负面影响,该研究结果可为垫料生产及使用单位在储存库房选址、 储存环境参数设定及质量控制体系构建等方面提供重要参考依据。

关键词: 高温高湿环境, 非灭菌性垫料, 卫生指标

Abstract: Objective To investigate the impact of different storage durations in a high temperature and high humidity environment on the hygienic indicators (microbial indicators and chemical pollutant indicators) of non-sterilized poplar wood shavings bedding,and to provide scientific data for temperature and humidity regulation as well as quality control during the bedding storage.Methods Non-sterilized poplar wood shavings bedding was randomly divided into Group A, Group B, and Group C. Samples were collected at 0 d, 7 d, 14 d, 21 d, and 28 d respectively to detect their microbial indicators and chemical pollutant indicators.Results There were significant differences in temperature and humidity among the three groups of storage environments. During the 0 d to 28 d storage period, the mold and yeast indicators of the bedding from three groups failed to meet the qualified standards.At 14 d, the Escherichia coli indicators of Group A and Group B were unqualified.At 21 d and 28 d, the Escherichia coli indicators of all three groups were unqualified.Conclusion High temperature and high humidity environment has a significant negative impact on the microbial indicators of non-sterilized bedding. The result of this study can provide important references for bedding production and use units in aspects such as the site selection of storage warehouses, the setting of storage environment parameters, and the construction of quality control systems.

Key words: high temperature and high humidity environment, non-sterilized bedding, hygienic indicators

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