关键词: 记忆障碍, 动物模型, 阿尔茨海默病, 帕金森病

Abstract: Memory impairment is the primary symptom of numerous neurological diseases and represents a hot and challenging issue in current neuroscience research. The development of animal models of memory impairment serves as the foundation for research on nervous system disorders. Multiple chemicals are utilized in the creation of memory impairment models due to their ability to interfere with or disrupt the function of biological macromolecules. This article comprehensively reviews the specific types and mechanisms of memory impairment induced by various chemicals, offering a theoretical basis for the study of memory impairment models and novel insights into exploring approaches to ameliorate memory impairment.

Key words: memory impairment, animal models, Alzheimer’s disease, Parkinson’s disease