关键词: CB6F1小鼠, B6CF1小鼠, 血生化, 脏器重量, 脏器系数

Abstract: Abstract To detect and compare blood biochemical, main organ weight and organ coefficient of CB6F1 and BCF1 mice. The blood of 40 CB6F1 mice and 40 B6CF1 mice (20 females and 20 males) in the 9th to 10th week were collected by picking eyeball, routine blood indicators were detected by an automatic hematology analyzer, and organ weight to calculate the organ coefficient were determined and analyzed. We compared blood biochemical indices, 11/14 indices were significant difference between male and female of CB6F1 mice, 9/14 indices were significant difference between male and female of B6CF1, 10/14 indices were significant difference between female CB6F1 mice and B6CF1 mice, 11/14 indices were significant difference between male CB6F1 mice and B6CF1 mice male (P < 0.05). Compared main organ weight and organ coefficient of CB6F1 and B6CF1 mice, there were significant difference in some indices for sex and lines (P < 0.05). There were partial differences in the blood biochemical, organ weight and organ coefficient of CB6F1 and BCF1 which were breeding by different female parent and male parent of BALB/c and C57BL/6 mice.

Key words: CB6F1 mice , BCF1 mice , blood biochemical , organ weight , organ coefficient