关键词: 聚焦声束超声, 恒河猴, 早孕, 月经, 生理学

Abstract: Objective\ The purpose of this paper is to study the influence on monkey,s generative physiology after terminating early pregnancy by focused ultrasound beams. Methods\ Five early pregnancy Macaque monkeys were treated with focused ultrasound beams, observing the recovery of menstruation and the change of skin after treatment, which show the hormone level.Two circles after the coming of menstruation, we estimated the shape and size of uterus and determined if there are some injuries on adjacent organs , by color Doppler ultrasonography (CDFI). Results\ Menstruation of these Macaque monkeys came 40 days after being treated with focused ultrasound beams to terminate the pregnancy, the volume and lasting period were normal, CDFI shows that the size and shape of uterus were normal, the endometrial line was clear to be observed, and there are no injuries on adjacent organs. Conclusion\ it is safe to terminate an early pregnancy of monkey model by Focused Ultrasound Beams, and there is no influence on the generative physiology, it has a potential prospect of being applied in clinics.

Key words: Focused ultrasound beams, Macaque, Early pregnancy, Menstruation, Physiology