关键词: 广西巴马小型猪, 培育

Abstract: Objective To develop a mini-pig strain with small body size, neat coat color, high reproductive performance and high genetic stability. Method 1) In the closed pur-bred breeding population (A strain), random mating method was used. 2) The animals of zero generation of inbreeding strain (B strain) was from the 10 th generations of closed pur-bred breeding group .The full-sib mating method was used to develop the inbreeding strain. 3) Directional selection was carried out in the selection programme. 4) The genetic stability was monitored by genetic marker analysis. 5) Some animal’s biological characters and nutritional requirement were determined. Results:1)The experimental mini-pig strain named as Guangxi Bama mini-pig was successfully developed in 1994 and continuous genetic breeding was carried out for 22 years. 2)The random mating had been continuously done for 21 generations in closed pur-bred breeding population until 2009. 3) The inbreeding strain had been cultivated for 11 generations until 2009. 4) Manifest selection progress was acquired on body size, neat coat color and reproductive performance. 5) The average observed number of 19 microsatellite loci in the 17 th generation of closed pure-bred population was 3.00. The average observed number of alleles,effective number of alleles and average rate of homozygous of 21 microsatellite loci in the 7 th generation of inbreeding group were 1.9048, 1.5461 and 0.7232, respectively. 6) The protein, digestible energy, calcium and available phosphorus requirement for the grower animal were determined to be 12%, 12.95Mj/kg, 0.65% and 0.32%, respectively. 7) The local standards of Guangxi Bama mini-pig strain proposed in the research was issued and published by the People's Government of Guangxi Zhuang Autonomous Region in 2008. 8) Guangxi Bama mini-pig was evaluated as excellent model animal in the study of cardiovascular diseases and diabetes by many research institutions in China. Conclusion We have successfully cultivated inbreeding and closed colony mini-pigs with unique characters, which are excellent laboratory animal used for medical and biological researches.

Key words: Guangxi Bama mini-pig, Genetic breeding