胚胎期颞下颌关节形态发育研究进展

doi:10.3969/j.issn.1006-6179.2024.04.014

实验动物科学 ›› 2024, Vol. 41 ›› Issue (4): 85-91.DOI: 10.3969/j.issn.1006-6179.2024.04.014

胚胎期颞下颌关节形态发育研究进展

( 1. 北京积水潭医院创伤骨科研究所动物实验室,北京 100035) ( 2. 中国食品药品检定研究院实验动物资源所,北京 102629)
( 3. 中国人民解放军总医院第一医学中心口腔科,北京 100853)

收稿日期:2022-11-14 出版日期:2024-08-28 发布日期:2024-08-28
通讯作者: 胡敏( 1956—) ,男,教授,主任医师,研究方向为口腔颌面外科,E-mail:humin48@ VIP. 163. com。
作者简介:相磊( 1982—) ,男,博士,高级兽医师,研究方向为实验动物学,E-mail:xianglei-322@ 163. com。王学文( 1979—) ,女,博士,高级兽医师,研究方向为实验动物学,E-mail:wangxuewen320@ 163. com。
基金资助:
北京市卫生健康委员会基金( BJRIO-RDP-2023)

Research Progress on Morphological Development of

Temporomandibular Joint During Embryonic Stage

( 1. Department of Animial Laboratory, Institute of Orthopaedic Trauma, Jishuitan Hospital, Beijing 100035,China)
( 2. Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control, Beijing 102629,China)
( 3. Department of Stomatology, the First Medical Center of PLA General Hospital, Beijing 100853,China)

Received:2022-11-14 Online:2024-08-28 Published:2024-08-28

摘要/Abstract

摘要：

颞下颌关节( TMJ)是哺乳动物特有的滑膜关节,其发育过程与长骨关节有着显著的不同。 TMJ 胚胎发育研

究已有近百年的历史,然而一方面人类 TMJ 胚胎发育研究的连续性受到限制,TMJ 发育起始以及髁突骨化与生长

方式等问题还尚未完全阐明;另一方面啮齿类动物作为 TMJ 发育研究的模式动物与人类 TMJ 还存在一定的差异,

寻求与人更为接近的模式动物开展 TMJ 胚胎发育研究的脚步从未停止。本文从人类与动物模型两个方面对胚胎

期 TMJ 的形态发育进行了综述。

关键词:

颞下颌关节, 胚胎发育, 模型动物

Abstract:

Temporomandibular joint ( TMJ) is a synovial joint unique to mammals and its development
process is significantly different from that of long bone joints. The study of embryonic development in TMJ
has nearly one hundred years history. However, on the one hand, the continuity of human TMJ embryo
development research is limited. The initiation of TMJ development and the condyle ossification and
growth patterns have not yet been fully elucidated in human. On the other hand, there are some
differences between rodents as model animals for TMJ development research and human. Seeking model
animals similar to human to carry out TMJ embryo development research has never stopped. This article
reviews the morphological development of embryonic TMJ including human and animal models.

Key words: temporomandibular joint, embryo development, animal model

中图分类号:

Q95-3

相磊王学文刘华蔚常平母晓丹胡敏.

胚胎期颞下颌关节形态发育研究进展

[J]. 实验动物科学, 2024, 41(4): 85-91.

XIANG Lei , WANG Xuewen , LIU Huawei , CHANG Ping , MU Xiaodan , HU Min .

Research Progress on Morphological Development of

Temporomandibular Joint During Embryonic Stage

[J]. Laboratory Animal Science, 2024, 41(4): 85-91.

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胚胎期颞下颌关节形态发育研究进展

Research Progress on Morphological Development of

Temporomandibular Joint During Embryonic Stage

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