关键词: 实验动物, 资源, 设施设备, 产业, 云南省

Abstract: Objective To systematically analyze the basic situation of laboratory animal resources in Yunnan Province, and to provide a scientific basis for the construction of laboratory animal innovation service system in Yunnan Province. Method A questionnaire and verification were used to survey the resources and industry distribution, production and use of laboratory animals, facility area and equipment investment, and employees of 44 laboratory animal institutions licensed before June 30, 2023, in Yunnan Province. Result All 44 questionnaires were retrieved. In Yunnan Province, laboratory animal institutions are distributed in 8 prefectures, and 54. 5% of them are enterprises, among which the biomedical industry accounts for the largest proportion (47. 7%) . There are a total of 79 licenses in the province, including 51 use licenses and 28 production licenses, with Kunming accounting for 72. 2% of  the licenses. 7 categories of laboratory animals and monkey feed are produced, and the production capacities of monkey feed, mice and specific pathogen-free( SPF) grade guinea pigs are 28. 8, 5. 6 and 3. 0 times respectively of the production volumes in 2022. 13 categories of laboratory animals are used, including mice, rats, guinea pigs and rabbits. The total area of laboratory animal facilities was 186 000 m 2 , of which production facilities accounted for 66 %, and the proposed facilities accounted for 71%. The total value of instruments and equipment for animal experiments accounts for 69%. From 2021 to 2023, there is an upward trend in the cost of operating the facility. 95% of full-time laboratory animal personnel hold training record cards. Conclusion It is necessary to lead the layout of experimental animal industrialization from the government level, establish an operation mechanism for experimental animal innovation and development in Yunnan Province, and enhance the ability of laboratory animals to serve scientific and technological innovation.

Key words: laboratory animals, resource, facilities and equipment, industrialization, Yunnan province