关键词: 实验动物, 动物模型, 科研范式, 问题凝练, 创新思维, 新视角

Abstract: Laboratory animals are one of the important basic research conditions that support technological innovation in fields such as life sciences and biomedicine. With the transformation of scientific research paradigms, accurately grasping the forefront of science and major national needs, further refining the difficulties and doubts in the creation and development of laboratory animal resources, is of great significance for accelerating the development of new varieties/ strains of laboratory animals and animal model creation and development. The paper reviews the construction and application of laboratory animal resources in China, and deeply explores the main problems in responding to the transformation of scientific research paradigms under the new situation. It also looks forward to new trends in the development of experimental animal resources in China, in order to provide a new perspective for the research and development of new experimental animal resources.

Key words: laboratory animals, animal models, research paradigm, problem condensation, innovative thinking;new perspective